Study could spur wider use of prenatal gene tests


A new study sets the stage for wider use of gene testing in early pregnancy. Scanning the genes of a fetus reveals far more about potential health risks than current prenatal testing does, say researchers who compared both methods in thousands of pregnancies nationwide.


A surprisingly high number — 6 percent — of certain fetuses declared normal by conventional testing were found to have genetic abnormalities by gene scans, the study found. The gene flaws can cause anything from minor defects such as a club foot to more serious ones such as mental retardation, heart problems and fatal diseases.


"This isn't done just so people can terminate pregnancies," because many choose to continue them even if a problem is found, said Dr. Ronald Wapner, reproductive genetics chief at Columbia University Medical Center in New York. "We're better able to give lots and lots of women more information about what's causing the problem and what the prognosis is and what special care their child might need."


He led the federally funded study, published in Thursday's New England Journal of Medicine.


A second study in the journal found that gene testing could reveal the cause of most stillbirths, many of which remain a mystery now. That gives key information to couples agonizing over whether to try again.


The prenatal study of 4,400 women has long been awaited in the field, and could make gene testing a standard of care in cases where initial screening with an ultrasound exam suggests a structural defect in how the baby is developing, said Dr. Susan Klugman, director of reproductive genetics at New York's Montefiore Medical Center, which enrolled 300 women into the study.


"We can never guarantee the perfect baby but if they want everything done, this is a test that can tell a lot more," she said.


Many pregnant women are offered screening with an ultrasound exam or a blood test that can flag some common abnormalities such as Down syndrome, but these are not conclusive.


The next step is diagnostic testing on cells from the fetus obtained through amniocentesis, which is like a needle biopsy through the belly, or chorionic villus sampling, which snips a bit of the placenta. Doctors look at the sample under a microscope for breaks or extra copies of chromosomes that cause a dozen or so abnormalities.


The new study compared this eyeball method to scanning with gene chips that can spot hundreds of abnormalities and far smaller defects than what can be seen with a microscope. This costs $1,200 to $1,800 versus $600 to $1,000 for the visual exam.


In the study, both methods were used on fetal samples from 4,400 women around the country. Half of the moms were at higher risk because they were over 35. One-fifth had screening tests suggesting Down syndrome. One-fourth had ultrasounds suggesting structural abnormalities. Others sought screening for other reasons.


"Some did it for anxiety — they just wanted more information about their child," Wapner said.


Of women whose ultrasounds showed a possible structural defect but whose fetuses were called normal by the visual chromosome exam, gene testing found problems in 6 percent — one out of 17.


"That's a lot. That's huge," Klugman said.


Gene tests also found abnormalities in nearly 2 percent of cases where the mom was older or ultrasounds suggested a problem other than a structural defect.


Dr. Lorraine Dugoff, a University of Pennsylvania high-risk pregnancy specialist, wrote in an editorial in the journal that gene testing should become the standard of care when a structural problem is suggested by ultrasound. But its value may be incremental in other cases and offset by the 1.5 percent of cases where a gene abnormality of unknown significance is found.


In those cases, "a lot of couples might not be happy that they ordered that test" because it can't give a clear answer, she said.


Ana Zeletz, a former pediatric nurse from Hoboken, N.J., had one of those results during the study. An ultrasound suggested possible Down syndrome; gene testing ruled that out but showed an abnormality that could indicate kidney problems — or nothing.


"They give you this list of all the things that could possibly be wrong," Zeletz said. Her daughter, Jillian, now 2, had some urinary and kidney abnormalities that seem to have resolved, and has low muscle tone that caused her to start walking later than usual.


"I am very glad about it," she said of the testing, because she knows to watch her daughter for possible complications like gout. Without the testing, "we wouldn't know anything, we wouldn't know to watch for things that might come up," she said.


The other study involved 532 stillbirths — deaths of a fetus in the womb before delivery. Gene testing revealed the cause in 87 percent of cases versus 70 percent of cases analyzed by the visual chromosome inspection method. It also gave more information on specific genetic abnormalities that couples could use to estimate the odds that future pregnancies would bring those risks.


The study was led by Dr. Uma Reddy of the National Institute of Child Health and Human Development.


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Online:


Medical journal: http://www.nejm.org


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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP


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Dow, S&P end higher, but Apple sinks Nasdaq in wild day

NEW YORK (Reuters) - A volatile trading session ended with U.S. stocks mostly higher on Wednesday, even as Apple, the most valuable company in the United States, suffered its worst day of losses in almost four years.


In a strange occurrence, Apple accounted for the entirety of the Nasdaq 100's <.ndx> fall of 1.1 percent, while the Dow industrials - which do not include Apple as a component - enjoyed the best day since November 28.


With the drop, Apple shed nearly $35 billion in market capitalization, its biggest one-day market-cap loss ever. The company's market value, or market capitalization, now stands at $506.85 billion.


"Today's move is because of index weightings, with the Nasdaq down because of Apple's decline," said Rex Macey, chief investment officer of Wilmington Trust in Atlanta. "The S&P is up because Apple isn't as big a weight in that index, and the Dow is up even more because it isn't there at all."


The broad market seesawed, with the S&P 500 dropping into negative territory before it rebounded off the 1,400 level, seen as a key support point over the past two weeks. Investors cited comments from President Barack Obama suggesting a potential near-term resolution to the "fiscal cliff" wrangling in Washington as a catalyst for the rebound.


Shares of The Travelers Cos Inc rose 4.9 percent to $74. The stock ranked as the Dow's top percentage gainer after the insurance company said it intended to resume stock buybacks it had temporarily suspended while it assessed its exposure to Superstorm Sandy. The company also said a preliminary estimate of net losses from Sandy was about $650 million after tax.


The Dow Jones industrial average <.dji> rose 82.71 points, or 0.64 percent, to 13,034.49 at the close. The Standard & Poor's 500 Index <.spx> gained 2.23 points, or 0.16 percent, to 1,409.28. But the Nasdaq Composite Index <.ixic> fell 22.99 points, or 0.77 percent, to end at 2,973.70.


Apple, the largest U.S. company by market capitalization and a big weight in both the S&P 500 and the Nasdaq, fell 6.4 percent to $538.79. Apple is down more than 20 percent from an all-time high reached in late September, putting the stock into bear market territory.


Banking shares were led higher by a 6.3 percent jump in Citigroup to $36.46 after the company said it would cut 4 percent of its workforce. The S&P financial sector index <.gspf> climbed 1.3 percent, and Bank of America hit a 52-week high of $10.55 before pulling back slightly. The stock, a Dow component, ended at $10.46, up 5.7 percent for the day.


Cyclical sectors, which are tied to the pace of economic growth, rallied on optimism about progress on a solution to avoid the fiscal cliff. An S&P index of industrial stocks <.gspi> rose 1.1 percent, buoyed by Caterpillar Inc , up 2.2 percent at $86.05, while an S&P index of energy shares <.gspe> climbed 0.7 percent. The Dow Jones Transportation Average <.djt> gained 0.9 percent, with CSX Corp jumping 2.7 percent to $20.16.


Still, Apple struggled throughout the session. Market participants cited a host of reasons for the drop in the iPad maker's stock, including a consultant's report about the company losing share in the tablet market and reports that margin requirements had been raised by at least one clearing firm, as well as year-end tax selling ahead of a possible rise in capital-gains tax rates next year.


On the Washington front, Obama told the Business Roundtable, a group of chief executives, on Wednesday that a fiscal cliff deal was possible "in about a week" if Republicans acknowledged the need to raise taxes on the wealthiest Americans.


Equities have struggled to gain ground recently because of concerns over the fiscal cliff - a series of mandatory spending cuts and tax increases effective in early January that could push the U.S. economy into recession next year. Recently equities have moved on any whiffs of sentiment from Washington in headlines about negotiations.


"Obama's comments generated a lot of optimism, but to the extent the market believes them, that's how much we're setting ourselves up for a decline if that deadline passes with no progress," said Macey, who helps oversee about $20 billion in assets.


In an interview on CNBC after the market closed, U.S. Treasury Secretary Tim Geithner said that uncertainty over the fiscal cliff was standing in the way of stronger economic growth, and that there was no prospect for an agreement if tax rates didn't rise on the wealthiest taxpayers.


The stock of Freeport-McMoRan Copper & Gold Inc fell 16 percent to $32.17 and ranked as the S&P 500's biggest percentage decliner. The company said it was acquiring Plains Exploration & Production Co and McMoRan Exploration Co in two separate deals for $9 billion in cash and stock in a major expansion into energy.


McMoRan Exploration soared 87 percent to $15.82 and Plains surged 23.4 percent to $44.50.


About half of the stocks traded on the New York Stock Exchange closed in positive territory, while about 54 percent of Nasdaq-listed shares ended lower.


Volume was higher than it has been in recent sessions, with about 6.93 billion shares changing hands on the New York Stock Exchange, the Nasdaq and NYSE MKT, above the daily average so far this year of about 6.48 billion shares.


(Editing by Jan Paschal)



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Typhoon Bopha Kills Hundreds in Philippines


Bullit Marquez/Associated Press


A resident hung clothing amid fallen trees and debris on Wednesday, a day after Typhoon Bopha made landfall in the village of Andap, in southern Philippines. More Photos »







MANILA — With many roads and bridges washed away, rescue teams struggled Wednesday to reach isolated villages in the southern Philippines after a powerful out-of-season typhoon tore through the region, leaving more than 270 people dead and hundreds more missing, officials said.




Typhoon Bopha packed winds of up to 100 miles per hour when it struck Tuesday, bringing torrential rains that washed away villages and left thousands homeless.


The deaths were concentrated in the province of Compostela Valley, a mountainous gold mining area, and the neighboring province of Davao Oriental, on the eastern coast of the southern Philippine island of Mindanao, Lt. Col. Lyndon Paniza, a military spokesman, said in a telephone interview late Wednesday afternoon.


A national disaster official, Benito Ramos, said at a news conference on Wednesday afternoon that 274 people had died, 339 were injured and 279 were missing. Those figures were likely to rise, he suggested, since rescue workers had not yet reached several villages in the hardest-hit areas and the casualties there were not known.


Most of the dead appeared to have drowned or been hit by falling trees or flying debris, officials said.


“There is debris in the road, so our soldiers are moving by foot,” Colonel Paniza said. “They are crossing rivers and landslides. I don’t want to speculate, but we don’t know what they will find when they reach those cut off areas.”


Three soldiers are known to have died, and eight are missing, he said. Some of the soldiers died when a landslide washed out their patrol base, and others disappeared while on search-and-rescue operations.


Local television crews broadcast grisly footage of mud-covered bodies being loaded into trucks in villages that appeared flattened by the storm. In some areas, not a single structure could be seen standing.


In areas where roads were washed out, the government sent seagoing vessels to take relief goods to remote coastal areas from the provincial capital of Davao Oriental, Mati.


“I have thus authorized the local government of Mati, its mayor and the provincial governor to use their calamity funds to hire all available large, local fishing boats for an immediate sea-lift transfer of goods to the affected areas,” Manuel Roxas, the interior secretary, said in a statement.


The eastern coast of Mindanao, which was the area hardest hit by the storm, is a remote, impoverished agricultural area. Mr. Roxas told reporters on Wednesday that during his visit to the area, he had seen tens of thousands of fallen coconut trees and many acres of destroyed banana plantations.


In New Bataan, the town hit hardest by the storm, Virgilia Babaag had been waiting nervously in her home before dawn on Tuesday as hard rain from the approaching typhoon pounded her small village.


“My neighbors started yelling, ‘The water is coming fast! Run! Run!’ ” she said Wednesday by telephone.


Ms. Babaag gathered up her three young nieces staying with her and ran through the night toward high ground. There she stayed with dozens of others as winds ripped through the town.


“When I came back, my roof was gone,” she said from her devastated home. “The houses around my place are destroyed. There are so many who have died here. The soldiers are still finding more.”


The Philippines is hit by as many as 20 powerful tropical storms each year, but this one struck remote communities south of the usual typhoon path.


“This is the first time that the people in this area have experienced a storm like this,” Colonel Paniza said. “They aren’t accustomed to big storms.”


Last December, Tropical Storm Washi — another out-of-season storm that hit south of the usual Philippine typhoon belt — killed more than 1,200 people and left hundreds of thousands homeless.


This year, officials put out strong warnings days in advance and carried out mandatory early evacuations of vulnerable communities.


President Benigno S. Aquino III, stung by criticism last year that the national government had not done enough to prepare for Tropical Storm Washi, went on television the day before the storm hit and pleaded with people to follow the instructions of local government officials.


“I am facing you now because the incoming storm is no laughing matter,” Mr. Aquino said, adding later, “We expect the cooperation of everyone so that nobody gets in harm’s way.”


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25 top-rated Facebook games from 2012












Games can be both a welcome and an annoying diversion on Facebook, the world’s most popular online social network. This year, Facebook crossed a big milestone — reaching 1 billion active users. Game companies such as “FarmVille” creator Zynga Inc. and Rovio Entertainment Ltd. of “Angry Birds” fame seek to tap into that vast base of users to gain more players for their games.


This week, Facebook Inc. issued a list of the 25 top-rated games that launched on Facebook in 2012. The company says the rankings are based on user ratings and engagement with the games. It’s the same methodology that Facebook uses to rank apps in its App Center.












Some of the games are played on Facebook’s website, while others are only on Apple Inc.‘s iOS or Google Inc.‘s Android devices using Facebook’s app.


Here’s the list:


1. “SongPop” (by FreshPlanet, on Facebook.com, iOS and Android)


2. “Dragon City” (by Social Point, on Facebook.com)


3. “Bike Race” (by Top Free Games, on iOS)


4. “Subway Surfers” (by Kiloo, on iOS and Android)


5. “Angry Birds Friends (by Rovio, on Facebook.com)


6. “FarmVille 2″ (by Zynga, on Facebook.com)


7. “Scramble with Friends” (by Zynga, on iOS)


8. “Clash of Clans” (by Supercell, on iOS)


9. “Marvel: Avengers Alliance” (by Playdom, on Facebook.com)


10. “Draw Something” (by Zynga, on iOS and Android)


11. “Hay Day” (by Supercell, on iOS)


12. “Baseball Heroes” (by Syntasia, on Facebook.com)


13. “ChefVille” (by Zynga, on Facebook.com)


14. “CSR Racing” (by NaturalMotion Games, on iOS)


15. “Candy Crush Saga” (by King.com, on Facebook.com and iOS)


16. “Matching With Friends” (by Zynga, on Facebook.com)


17. “Legend Online” (by Oasis Games, on Facebook.com)


18. “Jurassic Park Builder” (by Ludia, on Facebook.com)


19. “Dungeon Rampage” (by Rebel Entertainment, on Facebook.com)


20. “Pockie Ninja II Social” (by NGames Ltd., on Facebook.com)


21. “Jetpack Joyride” (by Halfbrick, on Facebook.com)


22. “Social Empires” (by Social Point, on Facebook.com and iOS)


23. “Bil ve Fethet” (by Peak Games, on Facebook.com)


24. “Ruby Blast Adventures” (by Zynga, on Facebook.com and iOS)


25. “Pyramid Solitaire Saga” (by King.com, on Facebook.com)


Social Media News Headlines – Yahoo! News


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Josh Lucas Says Sleep Training Son Was 'Incredibly Difficult'




Celebrity Baby Blog





12/04/2012 at 05:00 PM ET



Josh Lucas: Sleep Training Was 'Incredibly Difficult'
Paul Zimmerman/WireImage


No amount of tears, tantrums or extreme tiredness can deter new dad Josh Lucas from reveling in his most important role.


“Everyone says it’s the greatest adventure you’ll ever have and I’m amazed at how much I’m loving it,” the actor told PEOPLE during MoMA‘s benefit honoring Quentin Tarantino on Monday in New York City.


Recently, Lucas and his wife Jessica Henriquez set out to sleep train 5-month-old Noah Rev — and not even a week of wailing could affect his mood.


“It was incredibly difficult. The child is enraged and hates you,” the first-time father admits. “And yet you’re totally sleep-deprived and amazed by the experience — even when he’s screaming — of what you’re going through.”

Calling fatherhood a “beautiful thing,” Lucas has been busy bonding with his baby boy, including taking his son to see Wreck-It Ralph, Noah’s first movie theater experience.


“I took him to a Tiny Tots screening, which is where you’re allowed to bring your baby,” Lucas, 41, shares.


“He sat there with his mouth wide open. He literally watched 15 minutes with his mouth agape and then passed out like he’d been shot.”


– Anya Leon with reporting by Michelle Ward


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Study: Drug coverage to vary under health law


WASHINGTON (AP) — A new study says basic prescription drug coverage could vary dramatically from state to state under President Barack Obama's health care overhaul.


That's because states get to set benefits for private health plans that will be offered starting in 2014 through new insurance exchanges.


The study out Tuesday from the market analysis firm Avalere Health found that some states will require coverage of virtually all FDA-approved drugs, while others will only require coverage of about half of medications.


Consumers will still have access to essential medications, but some may not have as much choice.


Connecticut, Virginia and Arizona will be among the states with the most generous coverage, while California, Minnesota and North Carolina will be among states with the most limited.


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Online:


Avalere Health: http://tinyurl.com/d3b3hfv


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Wall Street slips as investors seek cliff progress

NEW YORK (Reuters) - Stocks finished slightly lower in a quiet session on Tuesday as the back-and-forth wrangling over the "fiscal cliff" gave investors little reason to act.


Trading volume was light as legislators continue to negotiate a deal to avoid a $600 billion package of tax hikes and federal spending cuts that would begin January 1 and could push the economy into recession.


Just 5.86 billion shares changed hands on the New York Stock Exchange, the Nasdaq and the NYSE MKT, below the year's daily average of 6.48 billion shares.


A key measure of investor anxiety has remained muted. The CBOE Volatility Index or VIX <.vix>, a gauge of market anxiety, was at 17.12, up 2.9 percent. It has not traded above 20 since July.


Optimism for progress was dented after remarks by President Barack Obama, who rejected a Republican proposal to resolve the crisis as "out of balance" and said any deal must include a rise in income tax rates on the wealthiest Americans.


"People don't know if what's going on is political posturing or real negotiations that represent progress," said Bernard Baumohl, managing director and chief global economist at the Economic Outlook Group in Princeton, New Jersey.


Expectations of higher taxes on dividends beginning in 2013 have pushed many companies to pay special dividends this year or advance their next payback to investors. Coach became the latest to move up the date of its next dividend payment, and the news lifted shares of the upscale leather-goods maker earlier in the session. By the close, though, Coach was down 1.2 percent at $57.52.


One of the S&P 500's top sectors for the day was health care <.gspa>, considered a defensive group.


The Dow Jones industrial average <.dji> fell 13.82 points, or 0.11 percent, to 12,951.78 at the close. The Standard & Poor's 500 Index <.spx> dipped 2.41 points, or 0.17 percent, to 1,407.05. The Nasdaq Composite Index <.ixic> shed 5.51 points, or 0.18 percent, to close at 2,996.69.


The market has been sensitive to rhetoric from Washington, as a failure to reach an agreement could send the U.S. economy back into recession. Still, many expect a resolution to be found, which could extend the S&P 500's rally of 12 percent so far this year.


Differences within the Republican Party came to the fore on Tuesday as one senator opposed to raising taxes lashed out at Republican House Speaker John Boehner for proposing to increase revenue by closing some tax loopholes.


Congressional Republicans recently proposed steep spending cuts to bring down the budget deficit, but gave no ground on Obama's call to raise tax rates on the rich. The proposal was quickly dismissed by the White House.


"We're on hold trying to figure it out, but investors are stressed since they have to make decisions soon about how to proceed with their investments if taxes are indeed going up. We could see a real pick-up in volume over the next week or so," Baumohl said.


Netflix Inc was the S&P 500's top percentage gainer, advancing 14 percent to $86.65 after Walt Disney Co agreed to give the company exclusive TV distribution rights to its movies, starting in 2016.


Intel Corp shares rose 2.2 percent to $19.97 after the top chipmaker sold $6 billion in bonds to fund stock buybacks and other business activities.


Darden Restaurants Inc shares plunged 9.6 percent to $47.40 as the S&P 500's worst performer after the company warned that its latest quarter would miss expectations after unsuccessful promotions led to a decline in sales at its Olive Garden, Red Lobster and LongHorn Steakhouse chains.


In contrast, Big Lots Inc surged 11.5 percent to $31.27 after the close-out retailer posted a smaller-than-expected loss and boosted its full-year adjusted earnings forecast.


MetroPCS Communications shares tumbled 7.5 percent to $9.96 after Sprint Nextel appeared unlikely to make a counter-offer for the wireless service provider.


Almost half of the stocks traded on the New York Stock Exchange closed lower, while 50 percent of Nasdaq-listed shares closed in negative territory.


After the closing bell, Pandora Media Inc


shares plunged 23 percent after the company reported its third-quarter results.

(Editing by Jan Paschal)

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U.S. Navy Denies Iranian Claim to Have Captured Drone





TEHRAN — Iran’s Revolutionary Guards Corps naval forces have captured an American drone that it said entered Iranian airspace over the Persian Gulf, state television reported on Tuesday. The claim was quickly denied by the United States Navy.




Iranian state media said the aircraft was a ScanEagle built by Boeing, which, according to the company’s Web site, can be launched and operated from ships.


A spokesman for the United States Navy in Bahrain denied the Iranian claim, saying that no American drones were missing.


“The U.S. Navy has fully accounted for all unmanned air vehicles operating in the Middle East region,” a spokesman for the United States Naval Forces Central Command in Bahrain told Reuters. “Our operations in the gulf are confined to internationally recognized water and airspace. We have no record that we have lost any ScanEagles recently.”


However, the drone could have been one used by the Central Intelligence Agency, or even the National Security Agency, which both have eyes on Iran. Several kingdoms of the Persian Gulf also have ScanEagle drones.


If the seizure is confirmed, it would indicate a spike in tension between the United States and Iran in the skies over the gulf. On Nov. 8, Pentagon officials said Iranian warplanes had fired at a Predator drone flying over the gulf the previous week. It was believed to be the first incident in which Iranian warplanes had fired on an American drone, they said.


State television showed images of what seemed to be an intact ScanEagle being inspected by Rear Adm. Ali Fadavi, the commander of the Revolutionary Guards’ naval forces. The drone was displayed in front of a large map of the Persian Gulf with a text in English and Persian saying, “We shall trample on the U.S.”


Without mentioning the drone claim, President Mahmoud Ahmadinejad on Tuesday warned Iran’s adversaries against aggression. “Our enemies should open their eyes,” he said in a speech. “They may be able to take a few steps forward, but in the end we will make them retreat behind their own border.”


Iran’s foreign minister, Ali Akbar Salehi, told state television on Tuesday that the country planned to use the capture of the drone as evidence against the United States in international organizations.


“We had announced to the Americans that according to international conventions, we would not allow them to invade our territories, but unfortunately they did not comply,” Mr. Salehi said. “We had objected to the Americans before, but they claimed they were not present in our territories. We will use this drone as evidence to pursue a legal case against American invasion in international forums.” Admiral Fadavi said his forces had “hunted down” the ScanEagle over the gulf after it violated Iranian airspace and had forced it to land electronically, the semiofficial Fars news agency reported. A state television commentator said the drone was on a spy mission.


A September report by the Government Accountability Office on unmanned aircraft systems warned that some drones were sensitive to jamming and spoofing. In a spoofing operation, an unencrypted GPS signal can be taken over by enemy forces, the report warns, effectively hijacking the drone.


A former member of Iran’s Foreign Policy and National Security Commission said the seizure of the drone illustrated Iran’s growing military powers and showed that the United States was not really interested in mending relations with Tehran.


“How can we trust President Obama for talks if he sends his drones into our airspace?” the former commission member, Heshmatollah Falahatpisheh, said in an interview. “This move is counterproductive for any détente.”


Iran’s Parliament, which always cheers on any success by the Revolutionary Guards, invited top commanders to present details of the capture to lawmakers.


“The hunting and capturing of this American drone once again showed off the defensive and repelling strengths of the Islamic republic to the world,” Ebrahim Aghamohammadi, a member of Parliament, told Fars. “We are moving forward with dominance.”


In the Nov. 1 attack on the Predator, American officials maintained that the drone had been over international waters, while Iranian commanders insisted that it had violated Iranian airspace. Sea and air borders in the region are strongly contested. Iranian naval forces in small speedboats and United States warships monitor the sea lanes, through which nearly 30 percent of the world’s oil is transported.


Last month, Iran complained to the United Nations over at least eight violations of its airspace by American planes.


Iran’s latest claim came 12 months after Iran said it had brought down an RQ-170 Sentinel operated by the C.I.A. At the time, Iranian state television showed images of the bat-winged drone — apparently fully intact — that Iran had nicknamed “the beast of Kandahar,” a reference to a drone base in Afghanistan.


Iran has maintained that it hacked into the RQ-170’s controls and forced it to land. But American officials said it had crashed in Iranian territory.


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Google updates Gmail for iOS to support multiple accounts, deliver autocomplete suggestions












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Snooki Gives Kate Middleton Motherhood Advice















12/04/2012 at 05:30 PM EST







Nicole Polizzi and Kate Middleton


Daniel Boczarski/WireImage; REX USA


Nicole "Snooki" Polizzi is lending her expertise to Kate Middleton – as a mommy mentor!

The Jersey Shore star, who gave birth to son Lorenzo in August, offered the expectant Duchess of Cambridge a few tips on being a new mom.

"It's hard, but don't stress out,” Polizzi told the New York Daily News. "Enjoy your pregnancy and be excited."

Middleton is currently in the hospital to treat her severe morning sickness, but Polizzi encouraged her to take it easy out of the public eye. “Enjoy your time at home – or the castle, in her case – with the baby,” she said. “Especially the first few months.”

Nobody said it would be easy, but Polizzi knows from experience that it's worth the (baby) bumps along the way.

"You'll get to know him/her, keep them safe and fall more in love each day," she says.

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